Search results for " food intake"
showing 10 items of 12 documents
Validation of a food frequency questionnaire for use in Italian adults living in Sicily.
2015
The objective of this study was to validate two interviewer-led food frequency questionnaires (FFQs) of very different lengths: a medium-length FFQ (medium-FFQ) of 36 items and a short-length FFQ (short-FFQ) of 18 items, intending to measure levels of intakes in a local population. Both FFQs were validated against intakes derived from a 3-day dietary record (3-day DR). Sixty-five non-diabetic adults with no known cardiovascular, renal or other systemic diseases were included. High correlation coefficients between the FFQ and the 3-day DR (0.45-0.73) were observed for energy intake, carbohydrates and lipid and protein intake. Bland-Altman plots showed good agreement between the methods. Low …
Food intake in lean and obese mice after peripheral administration of glucagon-like peptide 2
2012
We investigated the potential anorectic action of peripherally administered glucagon-like peptide 2 (GLP2) in lean and diet-induced obese (DIO) mice. Mice, fasted for 16 h, were injected i.p. with native GLP2 or [Gly2]GLP2, stable analog of GLP2, before or after GLP2 (3–33), a GLP2 receptor (GLP2R) antagonist, or exendin (9–39), a GLP1R antagonist. Food intake was measured at intervals 1, 2, 4, 8, and 24 h postinjection. In addition, we tested in lean mice the influence of [Gly2]GLP2 on gastric emptying and the effects of GLP1 alone or in combination with [Gly2]GLP2 on food intake. [Gly2]GLP2 dose dependently and significantly inhibited food intake in lean and DIO mice. The reduction of foo…
Neuronostatin: peripheral site of action in mouse stomach.
2015
Neuronostatin is a 13-amino acid peptide encoded by somatostatin gene. It is distributed in different organs including gastrointestinal tract and has been involved in the control of food intake and gastroin-testinal motility, likely through an action in the brain. So far, there are no reports about the occurrence of peripheral action sites in the gut. Therefore, the purpose of the present study was to examine, in the mouse, the effects of peripheral administration of neuronostatin on food intake within 24 h and on gastrointestinal motility and to analyse neuronostatin actions on the gastric and intestinal mechanical activity in isolated preparations in vitro. When compared with PBS-treated …
Peripheral Glucagon-like peptide 2 administration inhibits food intake in mice: Analysis of the mechanism of action.
2012
OBJECTIVE: Previously we showed that, in mice, peripheral administration of glucagon-like peptide 2 (GLP-2) or [Gly2]GLP-2, the degradation-resistant analogue of GLP-2, reduces food intake in the short term. The purposes of the present study were to compare the influence of [Gly2]GLP-2 with the anorectic effect induced by glucagon-like peptide 1 (GLP-1) and to analyze the mechanism of action responsible for GLP-2-induced effects. METHODS: Food intake was measured in mice, fasted for 16-18 h, at the first hour following peptide or vehicle intraperitoneally (i.p.) administration. The effects of GLP-2 (3-33), GLP-2 receptor (GLP-2R) antagonist, and exendin (9-39), GLP-1R antagonist were also e…
Factors Associated with Adherence to the Mediterranean Diet among Adolescents Living in Sicily, Southern Italy
2013
The present study aimed to examine the factors associated with increased Mediterranean diet (MD) adherence among a sample of Italian adolescents. A cross-sectional survey was conducted on 1135 students (13–16 years) attending 13 secondary schools of Sicily, southern Italy. Validated instruments were used for dietary assessment and the KIDMED score to assess adolescents’ adherence to the MD. A higher adherence to the MD was associated with high socioeconomic status (Odds Ratio [OR] 1.53, 95% Confidence Interval [CI]: 1.03–2.26) and high physical activity (OR 1.19, 95% CI: 1.02–1.70), whereas lower adherence was associated with living in an urban environment (OR 0.65, 95% CI: 0.44–0.97) and b…
Asperuloside Enhances Taste Perception and Prevents Weight Gain in High-Fat Fed Mice
2021
Asperuloside is an iridoid glycoside found in many medicinal plants that has produced promising anti-obesity results in animal models. In previous studies, three months of asperuloside administration reduced food intake, body weight, and adipose masses in rats consuming a high fat diet (HFD). However, the mechanisms by which asperuloside exerts its anti-obesity properties were not clarified. Here, we investigated homeostatic and nutrient-sensing mechanisms regulating food intake in mice consuming HFD. We confirmed the anti-obesity properties of asperuloside and, importantly, we identified some mechanisms that could be responsible for its therapeutic effect. Asperuloside reduced body weight …
Etude du contrôle hédonique de la prise alimentaire par l'analyse des potentiels évoqués gustatifs
2016
Hedonic control of food intake has been studied using neurophysiological investigations in animals and functional imaging in humans. Gustatory evoked potentials (GEPs), a higher time resolution technique than functional imaging, have never been used for this purpose. The first aim of this thesis was to establish a reliable recording of GEPs in humans, in response to a sapid stimulus. The second aim was to determine the GEPs modifications according to the hedonic value of food intake. GEPs recording was performed in response to an intermittent stimulation of a sapid solution in more than 100 young healthy subjects. The comparisons between cerebral recordings in response to water or paraffin …
High fat diet rapidly induces brain-plasticity-related transcriptomic signature in hypothalamus: role in energy homeostasis
2010
Poster board E12 (1 page) ; Session 203 - Food intake regulation 3 - Abstract n° 203.1 - Publication ref.: FENS Abstr., vol.5, 203.1, 2010; International audience; We have investigated the early events that are induced by a hypercaloric hyperlipidic diet in mice. The high fat diet rapidly induced metabolic imbalance, as soon as the first day, which is characterized. by a large increase in energy intake and several others metabolic alterations such as. hypercholesterolemia, and glucose intolerance. However, the diet-induced metabolic imbalance was. fully reversed after a week, suggesting that a physiological adaptive response has been then induced,. probably in order to counteract the delete…
Emerging Immnunohistochemical evidence for Direct Peripheral Control of Endocannabinoids on the Gastrointestinal Tract and Pancreas of Obese (fa/fa)a…
2012
This research has the objective to investigate immunohistochemical expression of CB1 receptor and its probable changes in Gastroenteropancreatic system (GEP) of obese and lean Zucker rats and understand the endocannabinoid pathophysiological implications in the obesity. Male obese (fa/fa) and lean Zucker rats 6 weeks old were obtained from Harlan Italy Srl; the rats were sacrificed at 8, 12 and 16 weeks old. Normal rats also were sacrificed. Specimens of stomach, jejunum-ileum and pancreas were fixed in Bouin’s mixture and embedded in paraffin; obtained sections were processed with anti-CB1 (Biosource Europe SA) by Streptavidin-Biotin-Complex Method. The findings show that CB1 receptor is e…
Psychometric evaluation of the Eating Disorders in Youth-Questionnaire when used in adults: Prevalence estimates for symptoms of avoidant/restrictive…
2020
Objective Restrictive eating behaviors occur across ages, but little is known about symptoms of avoidant/restrictive food intake disorder (ARFID), especially in adults. This study sought to examine the prevalence of symptoms of ARFID in the adult population, providing a psychometric evaluation of the Eating Disorders in Youth-Questionnaire (EDY-Q) and population norms. Method In a representative survey of the German population, N = 2,424 adults (1,297 women, 1,127 men; age 49.5 ± 17.5 years) were assessed with the EDY-Q and measures of eating disorder and general psychopathology for divergent validation. Results The point prevalence of self-reported symptoms of ARFID amounted to 0.8% (20/2,…